CD37 (Peripheral Mature B-Cell Marker) Antibody
Product Sizes
100 ug
£671.00
951-MSM1-P1-100UG
About this Product
- SKU:
- 951-MSM1-P1
- Additional Names:
- Tetraspanin-26
- Application:
- Flow Cytometry, Immunofluorescence
- translate.label.attr.clone:
- IPO-24
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes a protein of 33-55kDa; identified as CD37 (Workshop V; Code CD37.7). CD37 is strongly expressed on normal and neoplastic mature (sIg+) B-lymphocytes. In B-cell ontogeny; CD37 appears after the pre-B-cell stage; is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells.1 CD37 is also present; at low densities; on resting and activated T cells; neutrophils; monocytes; and some myelomonocytic leukemia cells. It is absent from platelets; erythrocytes. CD37 is a member of a family of tetraspan transmembrane proteins; including CD9; CD53; CD63; CD81; and CD82. It associates other tetraspan transmembrane proteins and MHC class II molecules to form a large complex at the surface of B cells and play a role in signal transduction. CD37 is a valuable and stable marker for peripheral mature B-cells and corresponding malignancies like B-cell chronic lymphocytic leukemia (B-CLL); hairy cell leukemia (HCL); and all types of B-cell non-Hodgkin'' lymphoma (B-NHL).
- Host:
- Mouse
- Immunogen:
- Spleen cells of a patient with hairy cell leukemia
- Isotype:
- IgG2b
- Molecular Weight:
- 33-55kDa
- Research Area:
- B Cell Markers; Cardiovascular
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=124744
