Recombinant CD34 (Hematopoietic Stem Cell & Endothelial Marker) Antibody
Product Sizes
100 ug
£671.00
947-MSM30-P1-100UG
About this Product
- SKU:
- 947-MSM30-P1
- Application:
- Immunohistochemistry, Western Blot
- translate.label.attr.clone:
- rHPCA1/8573
- Clonality:
- Monoclonal
- Extra Details:
- This MAb recognizes a single chain; transmembrane; heavily glycosylated protein of 90-120kDa; which is identified as CD34. On the basis of differential sensitivity to degradation by specific enzymes; epitopes of monoclonal antibodies to CD34 are classified into �three main categories; class I; class II and class III. It is a class II antibody whose epitope is resistant to neuraminidase but sensitive to glycoprotease and chymopapain. �CD34 expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition; CD34 is expressed by soft tissue tumors; such as solitary fibrous tumor and gastrointestinal stromal tumor. Its expression is also found in vascular endothelium. It appears that proliferating endothelial cells express this molecule more than the non-proliferating endothelial cells. Anti-CD34 labels > 85% of angiosarcoma and Kaposi s sarcoma; but with a lower specificity.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (around aa100-300) of human HPCA1 protein (exact sequence is proprietary)
- Isotype:
- IgG1
- Molecular Weight:
- 90-110kDa
- Research Area:
- Endothelial Cell Marker; Hematopoietic Stem Cells; Immunology; Mesenchymal Stem Cell Differentiation
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=128463
