CD86 (Dendritic Cells Maturation Marker) Antibody
Product Sizes
100 ug
£671.00
942-MSM16-P1-100UG
About this Product
- SKU:
- 942-MSM16-P1
- Additional Names:
- Activation B7-2 antigen | B70 | BU63 | CTLA-4 counter-receptor B7.2 | FUN-1
- Application:
- Immunohistochemistry, Western Blot
- translate.label.attr.clone:
- C86/3716
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes a protein of 70kDa; which is identified as CD86. CD86 is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is expressed at high levels on resting peripheral monocytes and dendritic cells and at very low density on resting B and T lymphocytes. CD86 expression is rapidly upregulated by B cell specific stimuli with peak expression at 18 to 42 hours after stimulation. CD86; along with CD80/B71; is an important accessory molecule in T cell co-stimulation via its interaction with CD28 and CD152/CTLA4. Since CD86 has rapid kinetics of induction; it is believed to be the major CD28 ligand expressed early in the immune response. It is also found on malignant Hodgkin and Reed Sternberg (HRS) cells in Hodgkin's disease.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (around aa 66-195) of human CD86 protein (exact sequence is proprietary)
- Isotype:
- IgG2b
- Molecular Weight:
- 70kDa
- Research Area:
- B Cell Markers; Cardiovascular; Cytokine Signaling; Dendritic Cell Marker; Hematopoietic Stem Cells; Immunology; Infectious Disease; Signal Transduction
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=124503
