CD80 (B7-1) Antibody
Product Sizes
20 ug
£364.00
941-MSM1-P0-20UG
About this Product
- SKU:
- 941-MSM1-P0
- Additional Names:
- Activation B7-1 antigen | BB1 | CTLA-4 counter-receptor B7.1
- Application:
- ELISA
- translate.label.attr.clone:
- C80/1608
- Clonality:
- Monoclonal
- Extra Details:
- T cell proliferation and lymphokine production are triggered by occupation of the TCR by antigen; followed by a costimulatory signal that is delivered by a ligand expressed on antigen presenting cells. The B7-related cell surface proteins CD80 (B7-1) and CD86 (B7-2) are expressed on antigen presenting cells bind the homologous T cell receptors CTLA-4 (cytotoxic T lymphocyte-associated protein-4) and CD28 and trigger costimulatory signals for optimal T cell activation. CTLA-4 shares 31% overall amino acid identity with CD28 and it has been proposed that CD28 and CTLA-4 are functionally redundant. SLAM is a novel receptor on T cells that; when engaged; potentiates T cell expansion in a CD28-independent manner. B7; also designated BB1; is another ligand or counter receptor for CD28 and CTLA-4 that is expressed on the antigen-presenting cell.
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human CD80 protein
- Isotype:
- IgG1
- Molecular Weight:
- 60kDa
- Research Area:
- AKT Signaling; B Cell Markers; Cardiovascular; Cytokine Signaling; Hematopoietic Stem Cells; Immune checkpoint; Immuno Oncology; Immunology; Infectious Disease; Signal Transduction
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=124471
