Recombinant MUC16 / CA125 (Ovarian Carcinoma Marker) Antibody
Product Sizes
100 ug
£671.00
94025-RBM3-P1ABX-100UG
About this Product
- SKU:
- 94025-RBM3-P1ABX
- Additional Names:
- Ovarian cancer-related tumor marker CA125 | Ovarian carcinoma antigen CA125
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- OCA125/2349R
- Clonality:
- Monoclonal
- Extra Details:
- The mucins are a family of highly glycosylated; secreted proteins with a basic structure consisting of a variable number of tandem repeats (VNTRs). Membrane-associated and secretory Mucins are high molecular weight glycoproteins of the glycocalyx (polysaccharide biofilm) that protects mucosal epithelium from particulate matter and microorganisms. Epithelial Mucins are large; secreted and cell surface glycoproteins crucial for adhesion modulation; signaling and epithelial cell protection. The number of repeats is highly polymorphic and varies among different alleles. The Mucin family consists of Mucins 1-4; Mucin 5 (AC and B); Mucins 6-8; Mucins 11-13 and Mucins 15-17. The Mucin 16 protein (also commonly referred to as CA125); encoded for by the gene MUC16; is a very high molecular weight tumor antigen consisting of three domains: a carboxy terminal domain; an extracellular domain and an amino terminal domain. Mucin 16; an ovarian cancer-associated antigen; is used as a marker to monitor the progress of epithelial ovarian cancer. It is a hydrophilic membrane-associated protein that may be involved in vitamin A functions.
- Host:
- Rabbit
- Immunogen:
- Purified human MUC16 protein
- Isotype:
- IgG
- Molecular Weight:
- >2|000kDa
- Research Area:
- Cancer; Immunology; Infectious Disease
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=124446
