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Antibodies

Recombinant MUC16 / CA125 (Ovarian Carcinoma Marker) Antibody

Product Sizes
100 ug
£671.00
94025-RBM3-P1-100UG
About this Product
SKU:
94025-RBM3-P1
Additional Names:
Ovarian cancer-related tumor marker CA125 | Ovarian carcinoma antigen CA125
Application:
Immunohistochemistry
translate.label.attr.clone:
OCA125/2349R
Clonality:
Monoclonal
Extra Details:
The mucins are a family of highly glycosylated; secreted proteins with a basic structure consisting of a variable number of tandem repeats (VNTRs). Membrane-associated and secretory Mucins are high molecular weight glycoproteins of the glycocalyx (polysaccharide biofilm) that protects mucosal epithelium from particulate matter and microorganisms. Epithelial Mucins are large; secreted and cell surface glycoproteins crucial for adhesion modulation; signaling and epithelial cell protection. The number of repeats is highly polymorphic and varies among different alleles. The Mucin family consists of Mucins 1-4; Mucin 5 (AC and B); Mucins 6-8; Mucins 11-13 and Mucins 15-17. The Mucin 16 protein (also commonly referred to as CA125); encoded for by the gene MUC16; is a very high molecular weight tumor antigen consisting of three domains: a carboxy terminal domain; an extracellular domain and an amino terminal domain. Mucin 16; an ovarian cancer-associated antigen; is used as a marker to monitor the progress of epithelial ovarian cancer. It is a hydrophilic membrane-associated protein that may be involved in vitamin A functions.
Host:
Rabbit
Immunogen:
Purified human MUC16 protein
Isotype:
IgG
Molecular Weight:
>2|000kDa
Research Area:
Cancer; Immunology; Infectious Disease
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody