Recombinant MUC16 / CA125 (Ovarian Carcinoma Marker) Antibody
Product Sizes
20 ug
£364.00
94025-RBM20-P0-20UG
About this Product
- SKU:
- 94025-RBM20-P0
- Additional Names:
- Ovarian cancer-related tumor marker CA125 | Ovarian carcinoma antigen CA125
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- CA125/13895R
- Clonality:
- Monoclonal
- Extra Details:
- CA125 also known as mucin 16; is a member of the mucin family glycoproteins. CA125 is a component of the ocular surface (including the cornea and conjunctiva); the respiratory tract and the female reproductive tract epithelia. Since CA125 is highly glycosylated it creates a hydrophilic environment that acts as a lubricating barrier against foreign particles and infectious agents on the apical membrane of epithelial cells. CA125 reacts with both normal tissues and neoplasms of fallopian tube; endometrium; endocervix and mesothelioma. It does not react with colon cancer. Normal tissues such as breast; liver; skin; kidney and spleen are also negative. Studies have shown that CA125 reacts with approximately 80% of epithelial ovarian neoplasms of serous; endometrioid; clear cell and undifferentiated types. No reactivity has been shown for mucinous ovarian tumors or in germ cell or hematopoietic tumors. This antibody is a useful aid for classification of a variety of tumors; such as some adenocarcinomas of the colon; breast carcinomas; malignant mesothelioma; uterine adenomatoid tumor; lung bronchoalveolar carcinoma; and ovarian endometrioid and serous carcinomas.
- Host:
- Rabbit
- Immunogen:
- Recombinant human MUC16 protein
- Isotype:
- IgG
- Molecular Weight:
- >2000kDa
- Research Area:
- Immunology; Infectious Disease
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=152297
