Adiponectin (Marker of Obesity) Antibody
Product Sizes
100 ug
£671.00
9370-MSM5-P1ABX-100UG
About this Product
- SKU:
- 9370-MSM5-P1ABX
- Additional Names:
- 30 kDa adipocyte complement-related protein | Adipocyte complement-related 30 kDa protein | Adipocyte; C1q and collagen domain-containing protein | Adipose most abundant gene transcript 1 protein | Gelatin-binding protein
- Application:
- ELISA, Western Blot
- translate.label.attr.clone:
- ADPN/4255
- Clonality:
- Monoclonal
- Extra Details:
- This MAb reacts with adiponectin; an adipocytokine. Adipocytokines are hormones produced in adipose tissue. Adiponectin is abundantly present in plasma and has insulin like effect on glucose levels in the blood. Plasma adiponectin levels are low in insulin resistant patients who are obese; have diabetes mellitus type 2 or HIV-lipodystrophy. In women adiponectin levels tend to be higher than in men; which may be due to androgens suppressing adiponectin levels. Furthermore; adiponectin and leptin are both indicated in regulating body weight through direct action on the hypothalamus; influencing appetite. Obese people have low adiponectin levels while levels in anorexia patients are high. Adiponectin acts as ligand for various receptors; two of which have been identified; one probably involved in carbohydrate assimilation; the other in tuning the rate of metabolism. (Hotta K; et al.) Clone ADPN/4255 is also used in a combination ELISA with clone ADPN/4256; acting as the detection antibody.
- Host:
- Mouse
- Immunogen:
- Synthetic peptide corresponding to the globular head region of the Adiponectin molecule.
- Isotype:
- IgG1
- Molecular Weight:
- 26-30kDa
- Research Area:
- Cardiovascular; Complement System; Developmental Biology; Mesenchymal Stem Cell Differentiation
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=124381
