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Antibodies

Adiponectin (Marker of Obesity) Antibody

Product Sizes
20 ug
£364.00
9370-MSM3-P0-20UG
About this Product
SKU:
9370-MSM3-P0
Additional Names:
30 kDa adipocyte complement-related protein | Adipocyte complement-related 30 kDa protein | Adipocyte; C1q and collagen domain-containing protein | Adipose most abundant gene transcript 1 protein | Gelatin-binding protein
Application:
Immunohistochemistry, Western Blot
translate.label.attr.clone:
ADPN/1370
Clonality:
Monoclonal
Extra Details:
This MAb reacts with adiponectin; an adipocytokine. Adipocytokines are hormones produced in adipose tissue. Adiponectin is abundantly present in plasma and has insulin like effect on glucose levels in the blood. Plasma adiponectin levels are low in insulin resistant patients who are obese; have diabetes mellitus type 2 or HIV-lipodystrophy. In women adiponectin levels tend to be higher than in men; which may be due to androgens suppressing adiponectin levels. Furthermore adiponectin and leptin are both indicated in regulating body weight through direct action on the hypothalamus; influencing appetite. Obese people have low adiponectin levels while levels in anorexia patients are high. Adiponectin acts as ligand for various receptors; two of which have been identified; one probably involved in carbohydrate assimilation; the other in tuning the rate of metabolism.
Host:
Mouse
Immunogen:
Recombinant human Adiponectin protein fragment (around aa 145-226) (exact sequence is proprietary)
Isotype:
IgG2b
Molecular Weight:
26-30kDa
Research Area:
Autophagy; Cardiovascular; Complement System; Developmental Biology; Hypoxia; Mesenchymal Stem Cell Differentiation
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody