Recombinant CD22 / BL-CAM (B-Cell Marker) Antibody
Product Sizes
100 ug
£671.00
933-RBM10-P1-100UG
About this Product
- SKU:
- 933-RBM10-P1
- Additional Names:
- B-lymphocyte cell adhesion molecule | Sialic acid-binding Ig-like lectin 2 | T-cell surface antigen Leu-14
- Application:
- Immunohistochemistry, Western Blot
- translate.label.attr.clone:
- BLCAM/8113R
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes a protein of 130-140kDa; identified as CD22 (also known as BL-CAM). CD22 expression is restricted to normal and neoplastic B cells and is absent from other haemopoietic cell types. In B-cell ontogeny; CD22 is first expressed in the cytoplasm of pro-B and pre-B cells; and on the surface as B cells mature to become IgD+. It is not expressed by plasma cells; CD22 is found highly expressed in follicular mantle and marginal zone B-cells; and while germinal center B-cells are relatively weak. CD22 is a member of the immunoglobulin superfamily and serves as an adhesion receptor for sialic acid-bearing ligands expressed on erythrocytes and all leukocyte classes. It also associates with tyrosine kinases and play a role in signal transduction and B-cell activation.
- Host:
- Rabbit
- Immunogen:
- Recombinant fragment (around aa1-200) of human BL-CAM/CD22 protein (exact sequence is proprietary)
- Isotype:
- IgG
- Molecular Weight:
- 130-140kDa
- Research Area:
- B Cell Markers; Cardiovascular; Dendritic Cell Marker; Hematopoietic Stem Cells; Immunology
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=129934
