CD20 / MS4A1 (B-Cell Marker) Antibody
Product Sizes
100 ug
£671.00
931-MSM2-P1-100UG
About this Product
- SKU:
- 931-MSM2-P1
- Additional Names:
- B-lymphocyte surface antigen B1 | Bp35 | Leukocyte surface antigen Leu-16 | Membrane-spanning 4-domains subfamily A member 1
- Application:
- Flow Cytometry, Immunofluorescence, Western Blot
- translate.label.attr.clone:
- L26
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes a protein of 30-33kDa; which is identified as CD20. Its epitope is located in the cytoplasmic domain of CD20 and was; therefore; ascribed as CD20cy in the 5th Workshop. CD20 is a non-Ig differentiation antigen of B-cells and its expression is restricted to normal and neoplastic B-cells; being absent from all other leukocytes and tissues. CD20 is expressed by pre B-cells and persists during all stages of B-cell maturation but is lost upon terminal differentiation into plasma cells. This MAb can be used for immunophenotyping of leukemia and malignant cells; B lymphocyte detection in peripheral blood and B cell localization in tissues. It reacts with the majority of B-cells present in peripheral blood and lymphoid tissues and their derived lymphomas. In lymphoid tissue; germinal center blasts and B-immunoblasts are particularly reactive. It is a reliable antibody for ascribing a B-cell phenotype in known lymphoid tissues. Rarely; CD20-positive T-cell lymphomas have been reported. Reactivity has also been noted with Reed-Sternberg cells in cases of Hodgkin s disease; particularly of lymphocyte predominant type.
- Host:
- Mouse
- Immunogen:
- Human tonsil B cells
- Isotype:
- IgG2a
- Molecular Weight:
- 33-37kDa
- Research Area:
- B Cell Markers; Hematopoietic Stem Cells
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=124263
