CD20 / MS4A1 (B-Cell Marker) Antibody
Product Sizes
100 ug
£671.00
931-MSM1-P1-100UG
About this Product
- SKU:
- 931-MSM1-P1
- Additional Names:
- B-lymphocyte surface antigen B1 | Bp35 | Leukocyte surface antigen Leu-16 | Membrane-spanning 4-domains subfamily A member 1
- Application:
- Flow Cytometry, Immunofluorescence, Western Blot
- translate.label.attr.clone:
- B9E9
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes a protein of 33-37kDa; identified as CD20 (Workshop V; Code CD20.12). B9E9 recognizes extracellular domain of CD20. The epitope is similar to or identical to that recognized by other CD20 antibodies including Leu-16 and B1. This MAb can be used for immunophenotyping of leukemia and malignant cells; B lymphocyte detection in peripheral blood; B cell localization in tissues and B lymphocyte purification by immunosorbent methods. CD20 is a non-Ig differentiation antigen of B-cells and its expression is restricted to normal and neoplastic B-cells; being absent from all other leukocytes and tissues. CD20 is expressed by pre B-cells and persists during all stages of B-cell maturation but is lost upon terminal differentiation into plasma cells. Protein passes through the membrane 4 times with both ends in cytoplasm and exposes one short and one longer loop to the external environment. CD20 is not glycosylated in resting B cells and its cytoplasmic domains are differentially phosphorylated upon activation. It acts as a calcium channel involved in B-cell activation and cell cycle progression.
- Host:
- Mouse
- Immunogen:
- Lymphoblastoid cell line Daudi
- Isotype:
- IgG2a
- Molecular Weight:
- 33-37kDa
- Research Area:
- B Cell Markers; Hematopoietic Stem Cells
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=124235
