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Antibodies

CD20 / MS4A1 (B-Cell Marker) Antibody

Product Sizes
0.5 ml at 100ug/ml
£671.00
931-MSM1-CF488-100T-0.5MLAT100UG
About this Product
SKU:
931-MSM1-CF488-100T
Additional Names:
B-lymphocyte surface antigen B1 | Bp35 | Leukocyte surface antigen Leu-16 | Membrane-spanning 4-domains subfamily A member 1
Application:
Flow Cytometry, Immunofluorescence
translate.label.attr.clone:
B9E9
Clonality:
Monoclonal
Extra Details:
Recognizes a protein of 33-37kDa; identified as CD20 (Workshop V; Code CD20.12). B9E9 recognizes extracellular domain of CD20. The epitope is similar to or identical to that recognized by other CD20 antibodies including Leu-16 and B1. This MAb can be used for immunophenotyping of leukemia and malignant cells; B lymphocyte detection in peripheral blood; B cell localization in tissues and B lymphocyte purification by immunosorbent methods. CD20 is a non-Ig differentiation antigen of B-cells and its expression is restricted to normal and neoplastic B-cells; being absent from all other leukocytes and tissues. CD20 is expressed by pre B-cells and persists during all stages of B-cell maturation but is lost upon terminal differentiation into plasma cells. Protein passes through the membrane 4 times with both ends in cytoplasm and exposes one short and one longer loop to the external environment. CD20 is not glycosylated in resting B cells and its cytoplasmic domains are differentially phosphorylated upon activation. It acts as a calcium channel involved in B-cell activation and cell cycle progression.
Host:
Mouse
Immunogen:
Lymphoblastoid cell line Daudi
Isotype:
IgG2a
Molecular Weight:
33-37kDa
Research Area:
B Cell Markers; Hematopoietic Stem Cells
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 4 to 8°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody