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Antibodies

CD19 (B-Lymphocyte Marker) Antibody

Product Sizes
20 ug
£364.00
930-MSM6-P0-20UG
About this Product
SKU:
930-MSM6-P0
Additional Names:
B-lymphocyte surface antigen B4 | Differentiation antigen CD19 | T-cell surface antigen Leu-12
Application:
ELISA, Flow Cytometry, Immunohistochemistry
translate.label.attr.clone:
CD19/3116
Clonality:
Monoclonal
Extra Details:
CD19 is a transmembrane glycoprotein that contains two extracellular immunoglobulin-like domains. CD19 is present in both benign and malignant B-cells and is considered to be the most reliable surface marker of this lineage over a wide range of maturational stages. In normal lymphoid tissue; CD19 is observed in germinal centers; in mantle zone cells; and in scattered cells of the inter-follicular areas. Anti-CD19 exhibits an overall immunoreactivity pattern similar to those of the antibodies against CD20 and CD22. However; in contrast to CD20; expression of CD19 is continuous throughout B-cell development and through terminal differentiation of B-cells into plasma cells. Anti-CD19 positivity is seen in the vast majority of B-cell neoplasms commonly at a lower intensity than normal B-cell counterparts. Plasma cell neoplasms are nearly always negative; as are T-cell neoplasms.
Host:
Mouse
Immunogen:
Recombinant fragment of human CD19 protein (around aa96-281) (exact sequence is proprietary)
Isotype:
IgG1
Molecular Weight:
95kDa
Research Area:
B Cell Markers; Cardiovascular; Complement System; Hematopoietic Stem Cells; Immune checkpoint; Immunology; Infectious Disease; Mesenchymal Stem Cell Differentiation; Signal Transduction
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody