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Antibodies

ZNF276 (Transcription Factor) Antibody

Product Sizes
100 ug
£671.00
92822-MSM1-P1ABX-100UG
About this Product
SKU:
92822-MSM1-P1ABX
Additional Names:
Zinc finger protein 477
Application:
ELISA, Flow Cytometry, Immunofluorescence
translate.label.attr.clone:
PCRP-ZNF276-1A5
Clonality:
Monoclonal
Extra Details:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions; most of which encompass some form of transcriptional activation or repression. ZNF276 is a 614 amino acid protein containing five C2H2- type zinc fingers and one zinc finger associated (ZAD) domain. Due to a loss of heterozygosity at the chromosomal location of the gene encoding ZNF276 in sporadic breast cancers; the ZNF276 gene has been targeted as a possible breast cancer tumor suppressor. The FANCA gene; which encodes a DNA repair protein; is situated at the same chromosomal location as the ZNF276 gene; suggesting a possible involvement of ZNF276 in the progression of Fanconi anemia; an autosomal recessive disorder which is caused by mutations in the gene encoding FANCA. There are two isoforms of ZNF276 that exist as a result of an alternative splicing event.
Host:
Mouse
Immunogen:
Recombinant full-length human ZNF276 protein
Isotype:
IgG2b
Molecular Weight:
~67kDa
Research Area:
Nuclear Marker
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody