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Antibodies

L-PLUNC Antibody

Product Sizes
20 ug
£364.00
92747-MSM1-P0-20UG
About this Product
SKU:
92747-MSM1-P0
Additional Names:
Long palate; lung and nasal epithelium carcinoma-associated protein 1 | von Ebner minor salivary gland protein
Application:
ELISA, Immunohistochemistry, Western Blot
translate.label.attr.clone:
LPLUNC1/3206
Clonality:
Monoclonal
Extra Details:
The upper respiratory tract is the main place of entry for pathogens to invade the body; and early recognition of bacterial products in this region is crucial for host defense. Palate lung nasal epithelial clone PLUNC (or LUNX) is an airway specific secretory protein that is expressed in epithelial tissues and submucosal glands of the oral cavity and upper respiratory tract of humans; mice; rats and cows. PLUNC binds to lipopolysaccharide (LPS) in nasal lavage fluid (NLF) which points to its role in the inflammatory response of the upper airways after exposure to irritants. Decreased levels of PLUNC occur in the NLF of smokers and people who have been exposed to reactive epoxy chemicals; indicating that long-term exposure to airway irritants impairs the production of PLUNC in the upper respiratory tract. Abnormal expression of PLUNC may influence susceptibility to nasopharyngeal carcinoma in the Chinese population.
Host:
Mouse
Immunogen:
Recombinant full-length human BPIFB1 protein
Isotype:
IgG1
Molecular Weight:
25kDa
Research Area:
Immunology
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody