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Antibodies

RPS6KA5 / MSK1 Antibody

Product Sizes
20 ug
£364.00
9252-MSM1-P0-20UG
About this Product
SKU:
9252-MSM1-P0
Additional Names:
90 kDa ribosomal protein S6 kinase 5 | Nuclear mitogen- and stress-activated protein kinase 1 | RSK-like protein kinase
Application:
Flow Cytometry, Immunofluorescence, Western Blot
translate.label.attr.clone:
PCRP-RPS6KA5-1A8
Clonality:
Monoclonal
Extra Details:
The family of ribosomal S6 kinases (Rsks); designated Rsk-1; Rsk-2 and Rsk-3; have been implicated as important signaling intermediates in response to a broad range of ligand-activated receptor tyrosine kinases. A unique feature common to the three members of the Rsk family is that each possesses two non-identical complete kinase catalytic domains. A related S6 kinase; p70 S6 kinase; functions to phosphorylate the S6 protein on ribosomal 40S subunits. p70 S6 kinase b shares high sequence homology with p70 S6 kinase; except in the carboxy terminus where it contains a proline-rich domain that may be involved in SH3 domain containing protein interactions. MSK1 (also designated RLPK) is related to Rsk and p70 S6 kinase family members and is thought to be structurally similar to Rsk family members; but it may be regulated by distinct mechanisms.
Host:
Mouse
Immunogen:
Recombinant full-length human RPS6KA5 protein
Isotype:
IgG2b
Molecular Weight:
~90kDa
Research Area:
Bladder Cancer; Cytokine Signaling; Developmental Biology; Immunology; MAPK Signaling; Nuclear Marker; Signal Transduction
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody