Recombinant CD8A (Cytotoxic / Suppressor T-Cell Marker) Antibody
Product Sizes
100 ug
£671.00
925-RBM13-P1ABX-100UG
About this Product
- SKU:
- 925-RBM13-P1ABX
- Additional Names:
- T-lymphocyte differentiation antigen T8/Leu-2
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- CD8/4391R
- Clonality:
- Monoclonal
- Extra Details:
- The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that serves as a coreceptor for TCR recognition of MHC class I associated peptides and supports CTL activation by binding to the MHC; while making no direct contact with the peptide.CD8 is expressed on cytotoxic suppressor T cells. It is expressed as a heterodimer of CD8伪 and CD8尾. CD8 is expressed on approximately one-third of peripheral blood T cells (the CD4-negative cells). CD8 has also been detected at a low level on some natural killer (NK) cells. In normal human tonsil; large numbers of CD8+ lymphocytes were present within the paracortex; occasionally positive cells were also identified within germinal centers and within the investing squamous epithelium. In other tissues; only lymphoid cells and cells of histiocyte lineage showed positive staining for CD8.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide corresponding to CD8α residues within aa135-235 of CD8α
- Isotype:
- IgG
- Molecular Weight:
- 32kDa
- Research Area:
- Cardiovascular; Dendritic Cell Marker; Hematopoietic Stem Cells; Immunology; PD-1 blockade immunotherapy
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=124113
