CD8A (Cytotoxic / Suppressor T-Cell Marker) Antibody
Product Sizes
100 ug
£671.00
925-MSM7-P1ABX-100UG
About this Product
- SKU:
- 925-MSM7-P1ABX
- Additional Names:
- T-lymphocyte differentiation antigen T8/Leu-2
- Application:
- Flow Cytometry, Immunofluorescence
- translate.label.attr.clone:
- RIV11
- Clonality:
- Monoclonal
- Extra Details:
- Cluster of Differentiation 8 (CD8) is a disulphide-linked heterodimer consisting of the unrelated 伪 and 尾 subunits. Each subunit is a glycoprotein composed of a single extracellular Ig-like domain; a polypeptide linker; a transmembrane part and a short cytoplasmic tail. On T cells; CD8 is the coreceptor for the T cell receptor (TCR); and these two distinct structures recognize the Antigen Major Histocompatibility Complex (MHC). Specifically; the Ig-like domain of CD8伪 interacts with the 伪3-domain of the MHC class I molecule. CD8 ensures specificity of the TCR antigen interaction; prolongs the contact between the T cell and the antigen presenting cell; and the 伪 chain recruits the tyrosine kinase Lck; which is essential for T cell activation.
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human CD8A protein
- Isotype:
- IgG1
- Molecular Weight:
- 32kDa
- Research Area:
- Cardiovascular; Dendritic Cell Marker; Hematopoietic Stem Cells; Immunology; PD-1 blockade immunotherapy
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=124112
