Recombinant CD7 (T-Cell Leukemia Marker) Antibody
Product Sizes
20 ug
£364.00
924-RBM19-P0-20UG
About this Product
- SKU:
- 924-RBM19-P0
- Additional Names:
- GP40 | T-cell leukemia antigen | T-cell surface antigen Leu-9 | TP41
- Application:
- Immunohistochemistry, Western Blot
- translate.label.attr.clone:
- CD7/8496R
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes a protein of 40kDa; identified as CD7 (also known as gp40; Leu9). CD7 is a member of the immunoglobulin gene superfamily. Its N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxyl-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T-lymphocytes; and T cell leukemia. It is also found on natural killer cells; a small subpopulation of normal B cells and on malignant B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes; expression of adhesion molecules; cytokine secretion and proliferation. CD7 associates directly with phosphoinositol 3'-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation.
- Host:
- Rabbit
- Immunogen:
- Recombinant fragment (around aa 72-175) of human CD7 protein (exact sequence is proprietary)
- Isotype:
- IgG
- Molecular Weight:
- 40kDa
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=127937
