Aurora B (Proliferation Marker) Antibody
Product Sizes
100 ug
£671.00
9212-MSM1-P1-100UG
About this Product
- SKU:
- 9212-MSM1-P1
- Additional Names:
- Aurora 1 | Aurora- and IPL1-like midbody-associated protein 1 | Aurora/IPL1-related kinase 2 | STK-1 | Serine/threonine-protein kinase 12 | Serine/threonine-protein kinase 5 | Serine/threonine-protein kinase aurora-B
- Application:
- Western Blot
- translate.label.attr.clone:
- AURKB/1521
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes a protein of 39kDa; which is identified as Aurora B. The serine/threonine protein kinase aurora B (Aurora B) is a chromosomal passenger protein critical for accurate chromosome segregation; cytokinesis; protein localization to the centromere and kinetochore; correct microtubule-kinetochore attachment; and regulation of the mitotic checkpoint. Aurora B forms a tight complex with inner centrosome protein and survivin. Inactivation of any of these proteins causes similar defects in chromosome segregation. A significant overexpression of Aurora B has been found in a variety of human tumors including non-small cell lung carcinoma; astrocytoma; seminoma and carcinomas of the colon; prostate; endometrium and thyroid. The expression level of Aurora B is associated with cell proliferation and prognosis in these tumors.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (around aa 89-251) of human Aurora B protein (exact sequence is proprietary)
- Isotype:
- IgG1
- Molecular Weight:
- 39kDa
- Research Area:
- Signal Transduction; Transcription Factors
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=123968
