CD5 (Mantle Cell Lymphoma Marker) Antibody
Product Sizes
100 ug
£671.00
921-MSM1-P1-100UG
About this Product
- SKU:
- 921-MSM1-P1
- Additional Names:
- Lymphocyte antigen T1/Leu-1
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- C5/473
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes a 67kDa transmembrane protein; which is identified as CD5. The CD5 antigen is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes; the main reactivity is observed in T cell areas. Anti-CD5 is a pan T-cell marker that also reacts with a range of neoplastic B-cells; e.g. chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL); mantle cell lymphoma; and a subset (~10%) of diffuse large B-cell lymphoma. CD5 aberrant expression is useful in making a diagnosis of mature T-cell neoplasms. Anti-CD5 detection is diagnostic in CLL/SLL within a panel of other B-cell markers; especially one that includes anti-CD23. Anti-CD5 is also very useful in differentiating among mature small lymphoid cell malignancies. In addition; anti-CD5 can be used in distinguishing thymic carcinoma (+) from thymoma (-). Anti-CD5 does not react with granulocytes or monocytes.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (around aa450-495) of human CD5 protein.
- Isotype:
- IgG1
- Molecular Weight:
- ~67kDa
- Research Area:
- B Cell Markers; Hematopoietic Stem Cells
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=123907
