CD4 (T-Helper/Inducer Cell Marker) Antibody
Product Sizes
20 ug
£364.00
920-MSM7-P0-20UG
About this Product
- SKU:
- 920-MSM7-P0
- Additional Names:
- T-cell surface antigen T4/Leu-3
- Application:
- ELISA
- translate.label.attr.clone:
- CD4/3027
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes a protein of 55kDa; identified as CD4. It is a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigens and is also a receptor for the human immunodeficiency virus. This protein is expressed not only in T lymphocytes; but also in B cells; macrophages; and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation; and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. The majority of peripheral T-cell lymphomas are derived from the T-helper/regulatory cell subset so that most mature T-cell neoplasms are CD4+/CD8-. Anti-CD4 is used in the immunohistochemical staining of lymphoproliferative disorders to evaluate tumors with CD4 aberrant expression.
- Host:
- Mouse
- Immunogen:
- Recombinant human CD4 protein fragment (around aa 245-392) (exact sequence is proprietary)
- Isotype:
- IgG2b
- Molecular Weight:
- 55kDa
- Research Area:
- AKT Signaling; Cardiovascular; Cytokine Signaling; Hematopoietic Stem Cells; Immunology; Infectious Disease
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=123903
