ZBED1 / DREF Antibody
Product Sizes
20 ug
£364.00
9189-MSM3-P0-20UG
About this Product
- SKU:
- 9189-MSM3-P0
- Additional Names:
- DNA replication-related element-binding factor | Putative Ac-like transposable element | Zinc finger BED domain-containing protein 1 | dREF homolog
- Application:
- Flow Cytometry, Immunofluorescence, Western Blot
- translate.label.attr.clone:
- PCRP-ZBED1-1E1
- Clonality:
- Monoclonal
- Extra Details:
- ZBED1 (zinc finger BED domain-containing protein 1); also known as ALTE (Ac-like transposable element); DREF or TRAMP; is a 694 amino acid protein that localizes specifically to granular structures within the nucleus. Expressed ubiquitously at low levels and present at higher levels in heart; placenta; spleen and skeletal muscle; ZBED1 is thought to function as a transcription factor that regulates a number of ribosomal protein (RP) encoding genes; thereby playing a role in the cell cycle and in cell proliferation events. ZBED1 contains one BED-type zinc finger and binds specifically to 5'- TGTCG[CT]GA[CT]A-3' DNA regions found in RP promotors. Additionally; ZBED1 binds strongly to the promotor region of Histone H1 (a protein required for the condensation of nucleosomes into higher order structures); subsequently activating H1 transcription.
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human ZBED1 protein
- Isotype:
- IgG2a
- Molecular Weight:
- 86kDa
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=123871
