Recombinant RCAS1 / Estrogen Receptor Binding Site Associated; Antigen 9 Antibody
Product Sizes
100 ug
£671.00
9166-RBM3-P1-100UG
About this Product
- SKU:
- 9166-RBM3-P1
- Additional Names:
- Cancer-associated surface antigen RCAS1 | Estrogen receptor-binding fragment-associated gene 9 protein
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- EBAG9/7033R
- Clonality:
- Monoclonal
- Extra Details:
- EBAG9; also known as RCAS1; is an estrogen-transcribed protein. Soluble and membranous RCAS1 proteins may play a role in the immune escape of tumor cells by promoting T lymphocyte inhibition of growth and apoptosis. RCAS1 is expressed in a wide variety of cancers; including uterine; ovarian; and lung cancer cells; and acts as a ligand for a putative receptor present on peripheral lymphocytes. RCAS1 is highly expressed not only in cancer cells but also in non-tumor bile duct cells subject to immune attack. RCAS1 inhibits the in vitro growth of receptor-expressing cells and induces apoptosis; contributing to the ability of tumor cells to evade host immune surveillance. High expression of RCAS1 significantly correlates with tumor progression and with poor outcome for many cancer patients.
- Host:
- Rabbit
- Immunogen:
- Recombinant human full-length EBAG9 protein
- Isotype:
- IgG
- Molecular Weight:
- 32kDa
- Research Area:
- Signal Transduction
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=123846
