CD3e (T-Cell Marker) Antibody
Product Sizes
100 ug
£671.00
916-MSM4-P1ABX-100UG
About this Product
- SKU:
- 916-MSM4-P1ABX
- Additional Names:
- T-cell surface antigen T3/Leu-4 epsilon chain
- Application:
- Flow Cytometry, Immunofluorescence, Immunohistochemistry
- translate.label.attr.clone:
- OKT3
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes the epsilon-chain of CD3; which consists of five different polypeptide chains (designated as gamma; delta; epsilon; zeta; and eta) with MW ranging from 16-28kDa. It is found on all mature T-lymphocytes; NK; T-cells; and some thymocytes. CD3; also known as T3; is a member of the immunoglobulin superfamily that plays a role in antigen recognition; signal transduction; and T cell activation. It is expressed; typically at high levels; on peripheral T cells and majority of T cell neoplasms. Thymocytes express CD3 at different level on the cell surface in the course of differentiation and; in cortical thymus; CD3 is predominantly Intracytoplasmic. This MAb has been reported to have potent immunosuppressive properties in vivo and has been proven effective in the treatment of renal; heart and liver allograft rejection.
- Host:
- Mouse
- Immunogen:
- Human PBMC s
- Isotype:
- IgG2a
- Molecular Weight:
- 23kDa
- Research Area:
- Cardiovascular; Hematopoietic Stem Cells; Immunology; PD-1 blockade immunotherapy
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=123812
