CD3e (T-Cell Marker) Antibody
Product Sizes
100 ug
£671.00
916-MSM14-P1-100UG
About this Product
- SKU:
- 916-MSM14-P1
- Additional Names:
- T-cell surface antigen T3/Leu-4 epsilon chain
- Application:
- ELISA, Flow Cytometry, Western Blot
- translate.label.attr.clone:
- C3e/2478
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes the epsilon-chain of CD3; which consists of five different polypeptide chains (designated as gamma; delta; epsilon; zeta; and eta) with MW ranging from 16-28kDa. The CD3 complex is closely associated at the lymphocyte cell surface with the T cell antigen receptor (TCR). Reportedly; CD3 complex is involved in signal transduction to the T cell interior following antigen recognition. The CD3 antigen is first detectable in early thymocytes and probably represents one of the earliest signs of commitment to the T cell lineage. In cortical thymocytes; CD3 is predominantly intra-cytoplasmic. However; in medullary thymocytes; it appears on the T cell surface. CD3 antigen is a highly specific marker for T cells; and is present in majority of T cell neoplasms.
- Host:
- Mouse
- Immunogen:
- Recombinant human CD3e fragment (around aa 23-119) (exact sequence is proprietary)
- Isotype:
- IgG1
- Molecular Weight:
- 20kDa
- Research Area:
- Cardiovascular; Hematopoietic Stem Cells; Immuno Oncology; Immunology; PD-1 blockade immunotherapy
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=123783
