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Antibodies

CD2 / Lymphocyte Function Antigen 2 (LFA-2) Antibody

Product Sizes
0.5 ml at 100ug/ml
£671.00
914-MSM3-CF488-100T-0.5MLAT100UG
About this Product
SKU:
914-MSM3-CF488-100T
Additional Names:
Erythrocyte receptor | LFA-2 | LFA-3 receptor | Rosette receptor | T-cell surface antigen T11/Leu-5
Application:
Flow Cytometry, Immunofluorescence
translate.label.attr.clone:
BH1
Clonality:
Monoclonal
Extra Details:
CD2 interacts through its amino-terminal domain with the extracellular domain of CD58 (also designated CD2 ligand) to mediate cell adhesion. CD2/CD58 binding can enhance antigen-specific T cell activation. CD2 is a transmembrane glycoprotein that is expressed on peripheral blood T lymphocytes; NK cells and thymocytes. CD58 is a heavily glycosylated protein with a broad tissue distribution in hematopoietic and other cells; including endothelium. Interaction between CD2 and its counter receptor LFA3 (CD58) on opposing cells optimizes immune system recognition; thereby facilitating communication between helper T lymphocytes and antigen-presenting cells; as well as between cytolytic effectors and target cells.
Host:
Mouse
Immunogen:
Human CD2 protein
Isotype:
IgG2b
Molecular Weight:
~50kDa
Research Area:
AKT Signaling; B Cell Markers; Hematopoietic Stem Cells
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody