CD2 / Lymphocyte Function Antigen 2 (LFA-2) Antibody

Product Sizes

100 ug

£671.00

914-MSM2-P1ABX-100UG

About this Product

SKU:: 914-MSM2-P1ABX
Additional Names:: Erythrocyte receptor | LFA-2 | LFA-3 receptor | Rosette receptor | T-cell surface antigen T11/Leu-5
Application:: Flow Cytometry, Immunofluorescence
translate.label.attr.clone:: UMCD2
Clonality:: Monoclonal
Extra Details:: CD2 interacts through its amino-terminal domain with the extracellular domain of CD58 (also designated CD2 ligand) to mediate cell adhesion. CD2/CD58 binding can enhance antigen-specific T cell activation. CD2 is a transmembrane glycoprotein that is expressed on peripheral blood T lymphocytes; NK cells and thymocytes. CD58 is a heavily glycosylated protein with a broad tissue distribution in hematopoietic and other cells; including endothelium. Interaction between CD2 and its counter receptor LFA3 (CD58) on opposing cells optimizes immune system recognition; thereby facilitating communication between helper T lymphocytes and antigen-presenting cells; as well as between cytolytic effectors and target cells.
Host:: Mouse
Immunogen:: Human Thymocytes/Sezary T cells
Isotype:: IgG2a
Molecular Weight:: ~50kDa
Research Area:: AKT Signaling; B Cell Markers; Hematopoietic Stem Cells
Shipping Conditions:: Blue Ice
Storage Conditions:: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:: NeoBiotechnologies
Type:: Antibodies: Monoclonal Antibody

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