CD1c Antibody
Product Sizes
100 ug
£671.00
911-MSM1-P1ABX-100UG
About this Product
- SKU:
- 911-MSM1-P1ABX
- Application:
- ELISA, Western Blot
- translate.label.attr.clone:
- CD1C/1603
- Clonality:
- Monoclonal
- Extra Details:
- The CD1 multigene family encodes five forms of the CD1 T-cell surface glycoprotein in human; designated CD1A; 1B; 1C; 1D and 1E. CD1; a type 1 membrane protein; has structural similarity to the MHC class I antigen and has been shown to present lipid antigens for recognition by T lymphocytes. CD1 antigens are associated with -2-Microglobulin and expressed on cortical thymocytes; Langerhans cells; a B cell subset and some dendritic cells. Specifically; CD1A is a marker for Langerhans cell histiocytosis (LCH) and is found on interdigitating cells. Adaptor-protein complexes and CD1-associated chaperones control CD1 trafficking; and the development and activation of CD1-restricted T cells. Constitutive endocytosis of CD1B molecules and the differential sorting of MHC class II from lysosomes separate peptide- and lipid antigen-presenting molecules during dendritic cell maturation. CD1B is also expressed in interdigitating cells. The human CD1 genes are all closely linked in a cluster mapping at chromosome 1q23.1
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human CD1c protein
- Isotype:
- IgG1
- Molecular Weight:
- 43kDa
- Research Area:
- B Cell Markers; Dendritic Cell Marker; Hematopoietic Stem Cells; Immunology
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=123696
