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Antibodies

CD1b (T-Cell Surface Glycoprotein) Antibody

Product Sizes
100 ug
£671.00
910-MSM2-P1BX-100UG
About this Product
SKU:
910-MSM2-P1BX
Application:
Flow Cytometry, Immunofluorescence
translate.label.attr.clone:
100-1A5
Clonality:
Monoclonal
Extra Details:
The Mouse monoclonal antibody recognizes CD1b; a 44kDa type I glycoprotein associated with beta2-microglobulin (Workshop IV; Code T015). It is expressed on dendritic cells; Langerhans cells; thymocytes; and T acute lymphoblastic leukemia cells. The CD1 multigene family encodes five forms of the CD1 T-cell surface glycoprotein in human; designated CD1A; 1B; 1C; 1D and 1E. CD1; a type 1 membrane protein; has structural similarity to the MHC class I antigen and has been shown to present lipid antigens for recognition by T lymphocytes. Constitutive endocytosis of CD1B molecules and the differential sorting of MHC class II from lysosomes separate peptide- and lipid antigen-presenting molecules during dendritic cell maturation. CD1B is also expressed in interdigitating cells.
Host:
Mouse
Immunogen:
Stimulated human leukocytes
Isotype:
IgM
Molecular Weight:
44kDa
Research Area:
Dendritic Cell Marker; Immunology
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody