Recombinant CD1a / HTA1 (Mature Langerhans Cells Marker) Antibody
Product Sizes
100 ug
£671.00
909-MSM8-P1-100UG
About this Product
- SKU:
- 909-MSM8-P1
- Additional Names:
- T-cell surface antigen T6/Leu-6
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- rC1A/711
- Clonality:
- Monoclonal
- Extra Details:
- At least five CD1 genes (CD1a; b; c; d; and e) are identified. CD1 proteins have been demonstrated to restrict T cell response to non-peptide lipid and glycolipid antigens and play a role in non-classical antigen presentation. CD1a is a non-polymorphic MHC Class 1 related cell surface glycoprotein; expressed in association with Beta-2 microglobulin. Anti-CD1a labels Langerhans cell histiocytosis (Histiocytosis X); extranodal histiocytic sarcoma; a subset of T-lymphoblastic lymphoma/leukemia; and interdigitating dendritic cell sarcoma of the lymph node. When combined with antibodies against TTF-1 and CD5; anti-CD1a is useful in distinguishing between pulmonary and thymic neoplasms since CD1a is consistently expressed in thymic lymphocytes in both typical and atypical thymomas; but only focally in 1/6 of thymic carcinomas and not in lymphocytes in pulmonary neoplasms. Anti-CD1a is reported to be a new marker for perivascular epithelial cell tumor (PEComa).
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human CD1a protein
- Isotype:
- IgG1
- Molecular Weight:
- 49kDa
- Research Area:
- Dendritic Cell Marker; Immunology
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=123667
