GPRC5A / PEIG-1 / RAI3 / RAIG1 / TIG1 Antibody
Product Sizes
20 ug
£364.00
9052-MSM1-P0-20UG
About this Product
- SKU:
- 9052-MSM1-P0
- Additional Names:
- G-protein coupled receptor family C group 5 member A | Phorbol ester induced gene 1 | Retinoic acid-induced gene 1 protein
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- GPRC5A/7893
- Clonality:
- Monoclonal
- Extra Details:
- Retinoic acid-induced protein 3 (RAI3) is an transmembrane G protein-coupled receptor that affects many essential biological processes including embryogenesis; cell growth; differentiation; and apoptosis. RAI3 may also be involved in maintaining homeostasis of epithelial cells. Retinoic acid receptors directly regulate RAI3 during its transcription in embryonal carcinoma differentiation. RAI3 expression is upregulated in most tumor cell lines that express mutant p53; suggesting that p53 interacts with the promoter of RAI3 and represses its expression at the beginning of apoptosis. RAI3 is a potential molecular target for diagnosing breast cancer; and selective suppression of signals from RAI3 may have a place in breast cancer treatments.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (around aa200-357) of human GPRC5A protein (exact sequence is proprietary)
- Isotype:
- IgG1
- Molecular Weight:
- 32kDa
- Research Area:
- Neuroscience
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=132330
