Recombinant Cyclin E (G1/S-Phase Cyclin) Antibody
Product Sizes
20 ug
£364.00
898-RBM5-P0-20UG
About this Product
- SKU:
- 898-RBM5-P0
- Application:
- Immunohistochemistry, Western Blot
- translate.label.attr.clone:
- CCNE1/4935R
- Clonality:
- Monoclonal
- Extra Details:
- Cyclin E belongs to the highly conserved cyclin family; whose members exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. Cyclins function as regulators of CDK kinases. Cyclin E forms a complex with and functions as a regulatory subunit of CDK2; whose activity is required for cell cycle G1/S transition. Cyclin E accumulates at the G1-S phase boundary and is degraded as cells progress through S phase. Cyclin E overexpression has been observed in many tumors; which results in chromosome instability; and thus may contribute to tumorigenesis.
- Host:
- Rabbit
- Immunogen:
- Recombinant human Cyclin E (CCNE1) protein fragment (around aa 10-176) (exact sequence is proprietary)
- Isotype:
- IgG
- Molecular Weight:
- 53kDa
- Research Area:
- Cardiovascular; Infectious Disease; Lung Cancer; Nuclear Marker; Signal Transduction; Transcription Factors
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=123636
