Recombinant BCL10 (MALT-Lymphoma Marker) Antibody
Product Sizes
20 ug
£364.00
8915-RBM3-P0-20UG
About this Product
- SKU:
- 8915-RBM3-P0
- Additional Names:
- B-cell CLL/lymphoma 10 | CARD-containing molecule enhancing NF-kappa-B | CARD-like apoptotic protein | CED-3/ICH-1 prodomain homologous E10-like regulator | Cellular homolog of vCARMEN | Cellular-E10 | Mammalian CARD-containing adapter molecule E10
- Application:
- Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot
- translate.label.attr.clone:
- BL10/2988R
- Clonality:
- Monoclonal
- Extra Details:
- BCL10; with an N-terminal caspase recruitment domain (CARD); is found in a number of apoptotic regulatory molecules. It was identified through its direct involvement in t(1;14) of mucosa-associated lymphoid tissue (MALT) lymphoma. Expression of BCL10 was shown to induce NF B activation in a NIK-dependent pathway. This MAb labels subpopulations of normal B and T cells and is a useful tool for the sub-classification of lymphomas. In MALT lymphomas with the t(1;14) translocation; while 55% of MALT lymphomas lacking this translocation exhibited the same labeling pattern; although at a much lower level.
- Host:
- Rabbit
- Immunogen:
- Recombinant human BCL10 protein fragment (around aa122-168) (exact sequence is proprietary)
- Isotype:
- IgG
- Molecular Weight:
- 33kDa
- Research Area:
- Apoptosis; Autophagy; Immunology
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=123607
