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Antibodies

Recombinant Cyclin A2 / CCNA2 (Marker of Tumor Proliferation) Antibody

Product Sizes
100 ug
£671.00
890-MSM6-P1-100UG
About this Product
SKU:
890-MSM6-P1
Additional Names:
Cyclin A
Application:
Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot
translate.label.attr.clone:
r6E6
Clonality:
Monoclonal
Extra Details:
It recognizes a protein of 54kDa; which is identified as cyclin A. Its epitope is located amino acids 144-148 of human Cyclin A2. Cyclins are regulatory subunits of the cyclin-dependent kinases (cdk's) and they control transition at different specific phases of the cell cycle. The temporal expression of cyclins is tightly regulated and subsequently plays a critical role in controlling the enzymatic activity of cdk's. These cyclin/cdk complexes are essential for passage through specific stages in the cell cycle. In mammalian somatic cells; cyclin A is required for S-phase and passage through G2-phase. The D and E type cyclins regulate the passage of G1; while cyclin B is a critical regulator of mitosis. Mutation or disruption of normal cyclin A expression causes cells to arrest in G2-phase.
Host:
Mouse
Immunogen:
Recombinant protein corresponding to the N-terminal fragment of cyclin A protein
Isotype:
IgG1
Molecular Weight:
54kDa
Research Area:
Hypoxia; Nuclear Marker; Transcription Factors
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody