TSC22D1 Antibody
Product Sizes
100 ug
£671.00
8848-MSM1-P1-100UG
About this Product
- SKU:
- 8848-MSM1-P1
- Additional Names:
- Cerebral protein 2 | Regulatory protein TSC-22 | TGFB-stimulated clone 22 homolog | Transforming growth factor beta-1-induced transcript 4 protein
- Application:
- Flow Cytometry, Immunofluorescence, Western Blot
- translate.label.attr.clone:
- PCRP-TSC22D1-1A2
- Clonality:
- Monoclonal
- Extra Details:
- Transforming growth factor 尾-stimulated acts as a transcriptional regulator to modulate cell growth and differentiation and cell death. TSC-22 contains a leucine zipper domain as well as a nuclear export signal; resulting in cytoplasmic localization in living cells. However; concomitant with the induction of apoptosis; TSC-22 translocates from the cytoplasm to the nucleus and shows transcriptional regulatory activity. TSC-22 acts as a major downstream component in the TGF尾 pathway and also the PPAR纬 signaling pathway. The association of these two pathways with tumor suppression; and the significant downregulation of TSC-22 mRNA in various cancer types; such as brain and salivary gland tumors; imply an antiproliferative role for TSC-22.
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human TSC22D1 protein
- Isotype:
- IgG1
- Molecular Weight:
- 16kDa
- Research Area:
- Nuclear Marker
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=123574
