Histone Deacetylase 1 (HDAC3) Antibody
Product Sizes
20 ug
£364.00
8841-MSM1-P0-20UG
About this Product
- SKU:
- 8841-MSM1-P0
- Additional Names:
- Protein deacetylase HDAC3 | Protein deacylase HDAC3 | RPD3-2 | SMAP45
- Application:
- ELISA, Flow Cytometry, Immunofluorescence
- translate.label.attr.clone:
- PCRP-HDAC3-2D4
- Clonality:
- Monoclonal
- Extra Details:
- In the intact cell; DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. Acetylation of lysine residues in the amino-terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA. Conversely; the deacetylation of histones is associated with transcriptional silencing. Several mammalian proteins have been identified as nuclear histone acetylases; including GCN5; PCAF (p300/CBP-associated factor); p300/CBP and the TFIID subunit TAF II p250. Mammalian HDAC1 (also designated HD1); HDAC2 (also designated RPD3) and HDAC3; all of which are related to the yeast transcriptional factor Rpd3p; have been identified as histone deacetylases.
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human HDAC3 protein
- Isotype:
- IgG2b
- Molecular Weight:
- 49kDa
- Research Area:
- Cardiovascular; Developmental Biology; Infectious Disease; Signal Transduction; Transcription Factors
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=123571
