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Antibodies

IL18R1 Antibody

Product Sizes
20 ug
£364.00
8809-MSM3-P0-20UG
About this Product
SKU:
8809-MSM3-P0
Additional Names:
CD218 antigen-like family member A | CDw218a | IL1 receptor-related protein | Interleukin-18 receptor alpha
Application:
Immunohistochemistry
translate.label.attr.clone:
IL18R1/7593
Clonality:
Monoclonal
Extra Details:
Interleukin-18 (IL-18) has been identified as a molecule that induces IFN-Î � production and enhances NK cell cytotoxicity. IL-18 receptor (IL-18R) is a type I membrane protein present in lung; leukocytes; spleen; liver; thymus; prostate; small intestine; colon; placenta and heart; and absent from brain; skeletal muscle; pancreas and kidney. IL-18R is present in Hodgkin s disease cell lines; and does not bind IL-1α or IL-1β. The association of IL-18 to IL-18R leads to activation of NFÎ �B. At present two subunits of IL-18R have been characterized: IL-18Rα and IL-18Rβ. IL-18Rα has been described as the ligand-binding chain and IL-18Rβ as the signal-transduction chain.
Host:
Mouse
Immunogen:
Recombinant fragment (around aa1-200) of human IL18R1 protein (exact sequence is proprietary)
Isotype:
IgG2
Molecular Weight:
62kDa
Research Area:
AKT Signaling; Cardiovascular; Cytokine Signaling; Immunology; Mitochondria Marker
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody