TRIM24 / TIF1 alpha Antibody
Product Sizes
100 ug
£671.00
8805-MSM2-P1-100UG
About this Product
- SKU:
- 8805-MSM2-P1
- Additional Names:
- E3 ubiquitin-protein ligase TRIM24 | RING finger protein 82 | RING-type E3 ubiquitin transferase TIF1-alpha | Tripartite motif-containing protein 24
- Application:
- Flow Cytometry, Immunofluorescence
- translate.label.attr.clone:
- PCRP-TRIM24-1B12
- Clonality:
- Monoclonal
- Extra Details:
- TIF1伪; also known as TRIM24; mediates transcriptional events by interactions with the AF2 region of several nuclear receptors; such as the estrogen; retinoic acid and vitamin D3 receptors. TIF1伪 localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. TIF1伪 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains (RING; B-box type 1 and B-box type 2) and a coiled-coil region. The TIF1伪 gene; which maps to human chromosome 7q33; encodes two alternatively spliced transcripts. However; the full length nature of one variant has not been determined. A TIF1伪 homolog (designated bonus) has been identified in Drosophila and is associated with several genes that are implicated in the ecdysone pathway; a nuclear hormone receptor pathway required throughout Drosophila development; suggesting a conserved functional role for the protein throughout the course of evolution.
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human TRIM24 protein
- Isotype:
- IgG1
- Molecular Weight:
- 117kDa
- Research Area:
- Infectious Disease; Nuclear Marker
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=123545
