Recombinant Sarcomeric Actinin Alpha 2 / ACTN2 Antibody
Product Sizes
100 ug
£671.00
88-MSM13-P1-100UG
About this Product
- SKU:
- 88-MSM13-P1
- Additional Names:
- Alpha-actinin skeletal muscle isoform 2 | F-actin cross-linking protein
- Application:
- Immunohistochemistry, Western Blot
- translate.label.attr.clone:
- rACTN2/8177
- Clonality:
- Monoclonal
- Extra Details:
- Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins; including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In non-muscle cells; the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions; where it is involved in binding actin to the membrane. In contrast; skeletal; cardiac; and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies; where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific; alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene.
- Host:
- Mouse
- Immunogen:
- A recombinant fragment (aa557-692) of human ACTN2 protein (exact sequence is proprietary)
- Isotype:
- IgG1
- Molecular Weight:
- 103kDa
- Research Area:
- Cardiovascular; Signal Transduction
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=134450
