CD137L / 4-1BBL / TNFSF9 Antibody
Product Sizes
0.5 ml at 100ug/ml
£671.00
8744-MSM1-B1-0.5MLAT100UG
About this Product
- SKU:
- 8744-MSM1-B1
- Additional Names:
- 4-1BB ligand
- Application:
- Flow Cytometry, Immunofluorescence, Immunohistochemistry
- translate.label.attr.clone:
- CD137L/1547
- Clonality:
- Monoclonal
- Extra Details:
- TNFSF9 / 4-1BBL is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9 / 4-1BB; which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9 / 4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. It has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine is required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines; and is thought to be involved in T cell-tumor cell interaction.
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human CD137L protein
- Isotype:
- IgG2a
- Molecular Weight:
- 27kDa
- Research Area:
- AKT Signaling; Cytokine Signaling; Immune checkpoint; Immunology
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=140574
