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Antibodies

Recombinant MRP3 (Multidrug Resistance-Associated Protein 3) Antibody

Product Sizes
100 ug
£671.00
8714-MSM5-P1-100UG
About this Product
SKU:
8714-MSM5-P1
Additional Names:
Canalicular multispecific organic anion transporter 2 | Multi-specific organic anion transporter D | Multidrug resistance-associated protein 3
Application:
Immunohistochemistry
translate.label.attr.clone:
rDTX1
Clonality:
Monoclonal
Extra Details:
The human multidrug resistance-associated protein (MRP) gene family contains at least 6 members designated MRP-1 to 6. MRP3 is a 190 to 200 kD integral membrane protein which is an organic anion transporter effective in transporting chemotherapeutic drugs such as MTX; etoposide and teniposide. Northern blotting of various human tissues has indicated MRP3 to be expressed in liver; colon; pancreas and at lower levels in the kidney. In liver; MRP3 is localized to the basolateral membrane of hepatocytes and is not associated with the canalicular membrane. MRP3 is also thought to play a role in bile production and secretion in the liver.
Host:
Mouse
Immunogen:
Recombinant prokaryotic fusion protein corresponding to a region of the cytoplasmic domains between transmembrane domains 11 and 12 of the MRP3 molecule
Isotype:
IgG2b
Molecular Weight:
169/137/55/32/65kDa
Research Area:
Metabolism
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody