ABCB11 / BSEP Antibody
Product Sizes
100 ug
£671.00
8647-MSM4-P1ABX-100UG
About this Product
- SKU:
- 8647-MSM4-P1ABX
- Additional Names:
- ATP-binding cassette sub-family B member 11
- Application:
- Immunohistochemistry, Western Blot
- translate.label.attr.clone:
- BSEP/7534
- Clonality:
- Monoclonal
- Extra Details:
- ATP-binding cassette (ABC) transporters are an evolutionarily conserved family of proteins that catalyze the transport of molecules across extra- and intracellular membranes through the energy of ATP hydrolysis. ABC genes comprise seven subfamilies; designated ABC1; Mdr/TAP; MRP; ALD; OABP; GCN20 and White. The secretion of bile salt molecules from blood into bile is a major driving force for bile formation. Bile salt export pump (BSEP) is a member of the Mdr/TAP subfamily of ABC transporters that mediates the transport of bile acids across the hepatocyte canalicular membrane and regulates bile acid-dependent bile secretion. BSEP contains putative phosphorylation sites for protein kinase A; protein kinase C (PKC) and Ca2+-calmodulin dependent kinase II; whose regulation may be dependent on bile salt concentration.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (around aa600-800) of human ABCB11 protein (exact sequence is proprietary)
- Isotype:
- IgG2b
- Molecular Weight:
- 160-190kDa
- Research Area:
- Cardiovascular; Infectious Disease
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=134784
