Recombinant p40 (Squamous; Basal & Myoepithelial Cell Marker) Antibody
Product Sizes
20 ug
£364.00
8626-RBM14-P0-20UG
About this Product
- SKU:
- 8626-RBM14-P0
- Additional Names:
- Chronic ulcerative stomatitis protein | Keratinocyte transcription factor KET | Transformation-related protein 63 | Tumor protein p73-like | p40 | p51
- Application:
- ELISA, Flow Cytometry, Immunohistochemistry
- translate.label.attr.clone:
- P40/4396R
- Clonality:
- Monoclonal
- Extra Details:
- p40 antibody (antibody recognizing Np63 only) is an isoform of p63; is thought to function as a stem cell factor; responsible for maintaining cells in an uncommitted state with regenerative potential a role that may be recapitulated in tumors derived from these cells. p40 is normally expressed in the basal or progenitor cell layer of stratified epithelia (eg. squamous; urothelial; bronchial); basal cells of some glandular epithelia (eg. prostate); as well as myoepithelial cells of breast and salivary glands; trophoblasts and thymic epithelial cells. In tumor tissues; p40 expression is specific for squamous cell carcinoma. p40 is equivalent to p63 in sensitivity for lung squamous cell carcinoma; but it is markedly superior to p63 in specificity; which eliminates a potential pitfall of misinterpreting a p63-positive adenocarcinoma or unsuspected lymphoma as squamous cell carcinoma. p40 appears to be a more reliable marker for squamous cell carcinoma.
- Host:
- Rabbit
- Immunogen:
- Recombinant fragment (around aa1-100) of human p40 protein (exact sequence is proprietary)
- Isotype:
- IgG
- Molecular Weight:
- 63kDa
- Research Area:
- Basal Cell Marker; Nuclear Marker; Stem Cell Differentiation; Transcription Factors
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=123457
