Recombinant p63 (Squamous; Basal & Myoepithelial Cell Marker) Antibody
Product Sizes
100 ug
£671.00
8626-RBM13-P1-100UG
About this Product
- SKU:
- 8626-RBM13-P1
- Additional Names:
- Chronic ulcerative stomatitis protein | Keratinocyte transcription factor KET | Transformation-related protein 63 | Tumor protein p73-like | p40 | p51
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- TP63/4379R
- Clonality:
- Monoclonal
- Extra Details:
- p63 is a homolog of the tumor suppressor p53. It is identified in basal cells in the epithelial layers of a variety of tissues; including epidermis; cervix; urothelium; breast and prostate. p63 was detected in nuclei of the basal epithelium in normal prostate glands; however; it was not expressed in malignant tumors of the prostate. As a result; p63 has been reported as a useful marker for differentiating benign from malignant lesions in the prostate; particularly when used in combination with markers of high molecular weight cytokeratins and the prostate-specific marker AMACR (P504S). p63 has also been shown to be a sensitive marker for lung squamous cell carcinomas (SqCC); with a sensitivity of ~90%. Specificity for lung SqCC; vs. lung adenocarcinoma (LADC); is approximately 80%. In breast tissue; p63 has been identified in myoepithelial cells of normal ducts.
- Host:
- Rabbit
- Immunogen:
- Recombinant fragment (around aa600-680) of human TP63 protein (exact sequence is proprietary)
- Isotype:
- IgG
- Molecular Weight:
- 63kDa
- Research Area:
- Basal Cell Marker; Nuclear Marker; Stem Cell Differentiation; Transcription Factors
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=123456
