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Antibodies

GTF2IRD2 Antibody

Product Sizes
100 ug
£671.00
84163-MSM1-P1ABX-100UG
About this Product
SKU:
84163-MSM1-P1ABX
Additional Names:
Transcription factor GTF2IRD2-alpha
Application:
Flow Cytometry, Western Blot
translate.label.attr.clone:
PCRP-GTF2IRD2-1B12
Clonality:
Monoclonal
Extra Details:
The TFII-I family contains two highly homologous 949 amino acid proteins; GTF2IRD2 (GTF2I repeat domain containing 2) and GTF2IRD2B (general transcription factor II-I repeat domain-containing protein 2B). Localizing to the nucleus; these proteins are ubiquitously expressed and contain two GTF2I- like repeats. Encoded by a gene mapping to human chromosome 7q11.23; GTF2IRD2 and GTF2IRD2B are located in the Williams-Beuren syndrome (WBS) critical region. The deletion of genes located within this region results in WBS; possibly due to the unequal crossing over of highly homologous low-copy repeat sequences that flank the deleted region. WBS is an autosomal dominant genetic condition that is characterized by physical; cognitive and behavioral traits including facial dysmorphology; vascular stenoses; growth deficiencies; dental anomalies and neurologic and musculoskeletal abnormalities.
Host:
Mouse
Immunogen:
Recombinant full-length human GTF2IRD2 protein
Isotype:
IgG2b
Molecular Weight:
107kDa
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody