Recombinant BAP1 (BRCA1 Associated Protein 1) Antibody
Product Sizes
100 ug
£671.00
8314-RBM17-P1-100UG
About this Product
- SKU:
- 8314-RBM17-P1
- Additional Names:
- BRCA1-associated protein 1 | Cerebral protein 6
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- BAP1/9120R
- Clonality:
- Monoclonal
- Extra Details:
- The BAP1 gene belongs to the ubiquitin C-terminal hydrolase subfamily of de-ubiquitination enzymes that are involved in the removal of ubiquitin from proteins. The encoded enzyme binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING finger domain of the latter and acts as a tumor suppressor. In addition; the enzyme may be involved in regulation of transcription; regulation of cell cycle and growth; response to DNA damage and chromatin dynamics. Germ line mutations in this gene may be associated with tumor predisposition syndrome (TPDS); which involves increased risk of cancers including malignant mesothelioma; Uveal melanoma and cutaneous melanoma.
- Host:
- Rabbit
- Immunogen:
- Recombinant fragment (around aa500-729) of human BAP1 protein (exact sequence is proprietary)
- Isotype:
- IgG
- Molecular Weight:
- 91kDa
- Research Area:
- Mesenchymal Stem Cell Differentiation; Nuclear Marker
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=132242
