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Antibodies

Eosinophil Peroxidase (EPX) Antibody

Product Sizes
100 ug
£671.00
8288-MSM1-P1ABX-100UG
About this Product
SKU:
8288-MSM1-P1ABX
Application:
Flow Cytometry, Immunofluorescence
translate.label.attr.clone:
AHE-1
Clonality:
Monoclonal
Extra Details:
Peripheral blood granulocytes are classified into neutrophils; basophils and eosinophils according to the staining characteristics of their cytoplasmic granules. Granule proteins are released by physiologic and pharmacologic stimuli and play important roles in both normal and pathological host immune responses. Eosinophil major basic protein and eosinophil peroxidase (EPX) are granule proteins specific to the eosinophil. AHE-1 recognizes human EPX; a granule protein specific to eosinophils. It does not cross-react with eosinophil major basic protein; elastase; cathepsin G; esterase N; thrombin; plasmin; kallikrein; lactoferrin; or transferrin. This MAb stains eosinophils only and does not stain other peripheral blood cells; including platelets; neutrophils; monocytes; lymphocytes or red blood cells. Human EPX gene product can form a tetramer of two light chains and two heavy chains. Other peroxidase family members include myeloperoxidase (MPO); lactoperoxidase (LPO); and thyroid peroxidase (TPO).
Host:
Mouse
Immunogen:
Human eosinophils from a patient with hypereosinophilic syndrome
Isotype:
IgG1
Molecular Weight:
70kDa (55kDa-Heavy Chain; 15kDa-Light Chain)
Research Area:
Immunology
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody