Calpain 1 Antibody
Product Sizes
20 ug
£364.00
823-MSM1-P0-20UG
About this Product
- SKU:
- 823-MSM1-P0
- Additional Names:
- Calcium-activated neutral proteinase 1 | Calpain mu-type | Calpain-1 large subunit | Cell proliferation-inducing gene 30 protein | Micromolar-calpain
- Application:
- ELISA, Immunohistochemistry
- translate.label.attr.clone:
- CAPN1/1530
- Clonality:
- Monoclonal
- Extra Details:
- Calpain 1 is an intracellular calcium-dependent protease that cleaves cytoskeletal and sub-membranous proteins. Calpains are non-lysosomal; calcium-activated intracellular cysteine proteases. Calpains mediate specific Ca2+- dependent processes including cell fusion; mitosis and meiosis. Calpains are heterodimers of a small regulatory subunit and one of three large catalytic subunits; designated Calpain 1; Calpain 2 and Calpain p94. Calpastatin regulates Calpain by inhibiting both the proteolytic activity of Calpain and its binding to membranes. Calpastatin exists in two types; tissue type and erythrocyte type; resulting from both alternative splicing and proteolytic processing. Calpain 1 co-localizes with human leukocyte antigen-DR (HLA-DR) on activated microglia in the aging brain. Calpain influences the process of spermatogenesis and the events preceding fertilization; such as the acrosome reaction.
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human CAPN1 protein
- Isotype:
- IgG1
- Molecular Weight:
- ~80kDa
- Research Area:
- Basal Cell Marker; Cardiovascular; Defective Intrinsic Apoptosis; Developmental Biology; Immunology; Infectious Disease; Neuroscience
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=123305
